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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EOMES
All Species:
21.52
Human Site:
S461
Identified Species:
39.44
UniProt:
O95936
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95936
NP_005433.2
686
72732
S461
F
R
D
N
Y
D
S
S
H
Q
I
V
P
G
G
Chimpanzee
Pan troglodytes
XP_001165803
690
73333
S465
F
R
D
N
Y
D
S
S
H
Q
I
V
P
G
G
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
S512
S
P
T
D
S
P
R
S
H
Q
I
V
P
G
G
Dog
Lupus familis
XP_850738
688
72729
S463
F
R
D
N
Y
D
S
S
H
Q
I
V
P
G
G
Cat
Felis silvestris
Mouse
Mus musculus
O54839
707
74783
S482
S
P
T
D
S
P
R
S
H
Q
I
V
P
G
G
Rat
Rattus norvegicus
XP_001061749
663
70857
S438
S
P
T
D
S
P
R
S
H
Q
I
V
P
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
E162
P
F
A
K
G
F
R
E
N
Y
D
V
M
F
S
Chicken
Gallus gallus
XP_426003
399
44936
S175
F
R
D
N
Y
D
S
S
H
Q
I
V
P
G
A
Frog
Xenopus laevis
P79944
692
75925
H468
P
A
D
S
P
R
S
H
Q
I
V
P
G
T
R
Zebra Danio
Brachydanio rerio
NP_571754
661
71990
F437
A
R
Y
A
M
Q
P
F
F
Q
D
Q
F
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
A605
H
A
H
Q
H
S
A
A
L
A
A
W
F
N
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
D197
L
H
V
V
R
C
A
D
R
H
N
L
M
Y
S
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
R572
S
K
N
V
T
V
S
R
N
S
C
P
A
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80
96.5
N.A.
87.5
81.6
N.A.
25.6
52.4
62.1
57.5
N.A.
22.9
N.A.
24.7
23.6
Protein Similarity:
100
99.1
82.9
96.9
N.A.
89.3
83.9
N.A.
33.5
54.5
70.5
68.9
N.A.
35.2
N.A.
34.9
37.9
P-Site Identity:
100
100
53.3
100
N.A.
53.3
53.3
N.A.
6.6
93.3
13.3
13.3
N.A.
0
N.A.
0
6.6
P-Site Similarity:
100
100
60
100
N.A.
60
60
N.A.
13.3
93.3
26.6
13.3
N.A.
20
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
8
8
0
0
16
8
0
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
39
24
0
31
0
8
0
0
16
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
31
8
0
0
0
8
0
8
8
0
0
0
16
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
8
54
47
% G
% His:
8
8
8
0
8
0
0
8
54
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
54
0
0
0
0
% I
% Lys:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
16
0
0
% M
% Asn:
0
0
8
31
0
0
0
0
16
0
8
0
0
8
8
% N
% Pro:
16
24
0
0
8
24
8
0
0
0
0
16
54
8
0
% P
% Gln:
0
0
0
8
0
8
0
0
8
62
0
8
0
0
0
% Q
% Arg:
0
39
0
0
8
8
31
8
8
0
0
0
0
0
8
% R
% Ser:
31
0
0
8
24
8
47
54
0
8
0
0
0
0
16
% S
% Thr:
0
0
24
0
8
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
8
16
0
8
0
0
0
0
8
62
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
8
0
31
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _